KEGG Pathway Analysis

The Kyoto Encyclopedia of Genes and Genomes (KEGG) is a comprehensive bioinformatics resource integrating genomic, pathway, disease, and other biological data. This tool enables functional enrichment analysis of your gene sets to identify significantly associated biological pathways and networks.

Uncover biological system functions and interactions through pathway analysis.

Input Data

Provide gene lists for KEGG pathway enrichment analysis.

Input Method

Gene List File

Upload a text file containing gene symbols or IDs (one per line or comma-separated).
Supported formats: .txt, .csv, .tsv

Gene Identification

Analysis Parameters

Configure parameters for KEGG pathway enrichment analysis.

Analysis Type

Pathway Categories

Select KEGG pathway categories to include in the analysis:

Statistical Parameters

log2(Ratio of gene counts)

Visualization Options

Enriched KEGG Pathways

Significantly enriched biological pathways identified in your gene list.

Cell cycle pathway visualization
Metabolism

Cell Cycle

hsa04110 | 28 genes

5.23 p = 1.2e-08
CDK1 CCNB1 TP53 +25
PI3K-Akt signaling pathway visualization
Environmental

PI3K-Akt signaling pathway

hsa04151 | 42 genes

4.87 p = 3.5e-07
PIK3CA AKT1 PTEN +39
MAPK signaling pathway visualization
Environmental

MAPK signaling pathway

hsa04010 | 36 genes

4.12 p = 7.8e-06
MAPK1 KRAS BRAF +33

Pathway Network Analysis

Networks of interconnected pathways and genes based on your enrichment results.

Pathway network visualization

Network Legend

Pathway Categories
Metabolism
Genetic Information
Environmental Information
Cellular Processes
P-value Scale
1e-10 1e-5 0.05

Lower p-values (more significant) in red

Interactions
Functional association
Component overlap
Regulatory relationship

Enrichment Visualizations

Visual representations of KEGG pathway enrichment results.

KEGG pathway enrichment bar chart

Visualization Controls

Analysis Results

Detailed results of KEGG pathway enrichment analysis and download options.

Significant Pathways

47

Significant Modules

23

Total Genes Analyzed

386

Genes Mapped to KEGG

247 (64%)

KEGG Pathway Enrichment Results

Pathway Name KEGG ID Category Gene Count Enrichment Score Adjusted p-value Genes Actions
Cell cycle hsa04110 Cellular Processes 28 5.23 1.2e-08
CDK1 CCNB1 +26
PI3K-Akt signaling pathway hsa04151 Environmental Information 42 4.87 3.5e-07
PIK3CA AKT1 +40
MAPK signaling pathway hsa04010 Environmental Information 36 4.12 7.8e-06
MAPK1 KRAS +34
Apoptosis hsa04210 Cellular Processes 19 3.89 2.1e-05
TP53 BCL2 +17
TGF-beta signaling pathway hsa04350 Environmental Information 15 3.24 4.7e-05
TGFB1 SMAD3 +13

Showing 1-5 of 47 results

Download Results